Gene information
Official symbol LEP
Official full name leptin
Gene type protein-coding gene
Chromosome7q32.1
Previous symbolOBS; OB
Gene familyNeuropeptides
Resources
Entrez Gene 3952
HGNC HGNC:6553
Ensembl ENSG00000174697
Vega OTTHUMG00000157564
UCSC uc003vml.3
GO terms: 376 records
GO Description Category LogP Number of genes Detail
GO:0001501 skeletal system development GO Biological Processes -17.2073293 69 More
GO:0001503 ossification GO Biological Processes -16.3087139 28 More
GO:0001525 angiogenesis GO Biological Processes -32.8794581 74 More
GO:0001568 blood vessel development GO Biological Processes -43.2646440 106 More
GO:0001666 response to hypoxia GO Biological Processes -40.6131384 77 More
GO:0001775 cell activation GO Biological Processes -43.3738118 71 More
GO:0001819 positive regulation of cytokine production GO Biological Processes -44.1872667 64 More
GO:0001890 placenta development GO Biological Processes -8.66149584 25 More
GO:0001910 regulation of leukocyte mediated cytotoxicity GO Biological Processes -7.82450130 11 More
GO:0001934 positive regulation of protein phosphorylation GO Biological Processes -52.8272623 84 More
GO:0001936 regulation of endothelial cell proliferation GO Biological Processes -54.5504306 75 More
GO:0001944 vasculature development GO Biological Processes -42.3240404 107 More
GO:0002021 response to dietary excess GO Biological Processes -4.59465180 5 More
GO:0002520 immune system development GO Biological Processes -15.2957169 80 More
GO:0002521 leukocyte differentiation GO Biological Processes -12.4650129 27 More
GO:0002694 regulation of leukocyte activation GO Biological Processes -32.0887020 60 More
GO:0002696 positive regulation of leukocyte activation GO Biological Processes -27.9249645 47 More
GO:0002697 regulation of immune effector process GO Biological Processes -33.2683521 48 More
GO:0002703 regulation of leukocyte mediated immunity GO Biological Processes -18.0432682 27 More
GO:0002706 regulation of lymphocyte mediated immunity GO Biological Processes -13.7265777 21 More
GO:0002715 regulation of natural killer cell mediated immunity GO Biological Processes -3.31185110 5 More
GO:0002790 peptide secretion GO Biological Processes -5.12832495 12 More
GO:0002791 regulation of peptide secretion GO Biological Processes -16.5189310 23 More
GO:0002792 negative regulation of peptide secretion GO Biological Processes -6.38368268 7 More
GO:0002831 regulation of response to biotic stimulus GO Biological Processes -10.931136 25 More
GO:0003012 muscle system process GO Biological Processes -27.3938503 63 More
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0003018 vascular process in circulatory system GO Biological Processes -47.1670528 52 More
GO:0003300 cardiac muscle hypertrophy GO Biological Processes -10.9367469 14 More
GO:0005179 hormone activity GO Molecular Functions -33.3562443 33 More
GO:0005975 carbohydrate metabolic process GO Biological Processes -4.30473825 38 More
GO:0005996 monosaccharide metabolic process GO Biological Processes -2.87918856 8 More
GO:0006006 glucose metabolic process GO Biological Processes -4.31450208 8 More
GO:0006066 alcohol metabolic process GO Biological Processes -16.7128396 29 More
GO:0006091 generation of precursor metabolites and energy GO Biological Processes -5.87282466 19 More
GO:0006109 regulation of carbohydrate metabolic process GO Biological Processes -13.1742479 35 More
GO:0006111 regulation of gluconeogenesis GO Biological Processes -5.35833465 7 More
GO:0006112 energy reserve metabolic process GO Biological Processes -4.0688237 6 More
GO:0006468 protein phosphorylation GO Biological Processes -5.36604576 56 More
GO:0006631 fatty acid metabolic process GO Biological Processes -20.3287405 33 More
GO:0006820 anion transport GO Biological Processes -2.9816627 14 More
GO:0006869 lipid transport GO Biological Processes -16.6388990 29 More
GO:0006909 phagocytosis GO Biological Processes -7.82039874 17 More
GO:0007159 leukocyte cell-cell adhesion GO Biological Processes -16.8529519 16 More
GO:0007259 receptor signaling pathway via JAK-STAT GO Biological Processes -5.73581155 7 More
GO:0007276 gamete generation GO Biological Processes -2.03816629 18 More
GO:0007292 female gamete generation GO Biological Processes -4.09618363 9 More
GO:0007548 sex differentiation GO Biological Processes -7.13021119 33 More
GO:0007565 female pregnancy GO Biological Processes -18.4002911 25 More
GO:0007584 response to nutrient GO Biological Processes -29.4823239 48 More
GO:0007586 digestion GO Biological Processes -7.00342423 19 More
GO:0007610 behavior GO Biological Processes -18.1916656 76 More
GO:0007623 circadian rhythm GO Biological Processes -8.17635164 13 More
GO:0007631 feeding behavior GO Biological Processes -8.63374021 12 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008202 steroid metabolic process GO Biological Processes -19.3229835 29 More
GO:0008203 cholesterol metabolic process GO Biological Processes -19.4799126 22 More
GO:0008217 regulation of blood pressure GO Biological Processes -35.2019435 60 More
GO:0008406 gonad development GO Biological Processes -5.85435513 14 More
GO:0008585 female gonad development GO Biological Processes -5.58425106 9 More
GO:0009100 glycoprotein metabolic process GO Biological Processes -1.91494967 10 More
GO:0009306 protein secretion GO Biological Processes -3.41168073 7 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0009743 response to carbohydrate GO Biological Processes -20.6536066 44 More
GO:0009895 negative regulation of catabolic process GO Biological Processes -10.3621088 43 More
GO:0009914 hormone transport GO Biological Processes -6.35710158 16 More
GO:0009991 response to extracellular stimulus GO Biological Processes -42.2178323 102 More
GO:0010506 regulation of autophagy GO Biological Processes -5.54010569 34 More
GO:0010507 negative regulation of autophagy GO Biological Processes -5.02981223 8 More
GO:0010675 regulation of cellular carbohydrate metabolic process GO Biological Processes -9.60411715 27 More
GO:0010817 regulation of hormone levels GO Biological Processes -29.5190556 49 More
GO:0010827 regulation of glucose transmembrane transport GO Biological Processes -18.4601079 28 More
GO:0010829 negative regulation of glucose transmembrane transport GO Biological Processes -8.17037988 10 More
GO:0010876 lipid localization GO Biological Processes -20.1994935 34 More
GO:0010883 regulation of lipid storage GO Biological Processes -22.5241589 19 More
GO:0010888 negative regulation of lipid storage GO Biological Processes -13.5596033 10 More
GO:0010906 regulation of glucose metabolic process GO Biological Processes -10.3110629 25 More
GO:0010942 positive regulation of cell death GO Biological Processes -48.7037743 123 More
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling GO Biological Processes -15.9250248 30 More
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling GO Biological Processes -18.2876323 28 More
GO:0014823 response to activity GO Biological Processes -19.5783025 27 More
GO:0014896 muscle hypertrophy GO Biological Processes -12.7837947 16 More
GO:0014897 striated muscle hypertrophy GO Biological Processes -10.7141263 14 More
GO:0015711 organic anion transport GO Biological Processes -3.37633297 12 More
GO:0015718 monocarboxylic acid transport GO Biological Processes -6.61280961 10 More
GO:0015833 peptide transport GO Biological Processes -4.22542842 7 More
GO:0015980 energy derivation by oxidation of organic compounds GO Biological Processes -4.48580735 13 More
GO:0016042 lipid catabolic process GO Biological Processes -9.62855375 20 More
GO:0016054 organic acid catabolic process GO Biological Processes -2.82368006 9 More
GO:0016125 sterol metabolic process GO Biological Processes -19.5624674 23 More
GO:0018108 peptidyl-tyrosine phosphorylation GO Biological Processes -3.43405510 8 More
GO:0018212 peptidyl-tyrosine modification GO Biological Processes -3.37492500 8 More
GO:0019216 regulation of lipid metabolic process GO Biological Processes -24.8423986 38 More
GO:0019218 regulation of steroid metabolic process GO Biological Processes -14.2494824 17 More
GO:0019221 cytokine-mediated signaling pathway GO Biological Processes -27.5840932 43 More
GO:0019229 regulation of vasoconstriction GO Biological Processes -25.9471687 22 More
GO:0019318 hexose metabolic process GO Biological Processes -3.25353717 8 More
GO:0019751 polyol metabolic process GO Biological Processes -1.55456673 9 More
GO:0021700 developmental maturation GO Biological Processes -12.5205714 23 More
GO:0021953 central nervous system neuron differentiation GO Biological Processes -5.15897962 21 More
GO:0021954 central nervous system neuron development GO Biological Processes -2.16280095 9 More
GO:0022407 regulation of cell-cell adhesion GO Biological Processes -32.4337382 53 More
GO:0022409 positive regulation of cell-cell adhesion GO Biological Processes -25.7751074 39 More
GO:0022600 digestive system process GO Biological Processes -8.16734280 17 More
GO:0022602 ovulation cycle process GO Biological Processes -5.5402655 7 More
GO:0023061 signal release GO Biological Processes -5.50151396 21 More
GO:0030072 peptide hormone secretion GO Biological Processes -4.51947106 11 More
GO:0030073 insulin secretion GO Biological Processes -2.93877642 4 More
GO:0030097 hemopoiesis GO Biological Processes -14.1443585 71 More
GO:0030098 lymphocyte differentiation GO Biological Processes -7.22308617 17 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030217 T cell differentiation GO Biological Processes -5.22709721 11 More
GO:0030258 lipid modification GO Biological Processes -3.55367288 9 More
GO:0030282 bone mineralization GO Biological Processes -8.89624301 10 More
GO:0030300 regulation of intestinal cholesterol absorption GO Biological Processes -4.56141436 5 More
GO:0030534 adult behavior GO Biological Processes -6.59104580 21 More
GO:0030545 signaling receptor regulator activity GO Molecular Functions -87.4728446 102 More
GO:0030546 signaling receptor activator activity GO Molecular Functions -90.4065983 101 More
GO:0030728 ovulation GO Biological Processes -8.85891522 7 More
GO:0031214 biomineral tissue development GO Biological Processes -8.35916144 12 More
GO:0031330 negative regulation of cellular catabolic process GO Biological Processes -6.88355184 32 More
GO:0031341 regulation of cell killing GO Biological Processes -10.2641102 14 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031667 response to nutrient levels GO Biological Processes -41.8130555 98 More
GO:0031668 cellular response to extracellular stimulus GO Biological Processes -10.2327580 36 More
GO:0031669 cellular response to nutrient levels GO Biological Processes -9.42886914 32 More
GO:0031670 cellular response to nutrient GO Biological Processes -9.31154255 13 More
GO:0032006 regulation of TOR signaling GO Biological Processes -2.04363613 5 More
GO:0032096 negative regulation of response to food GO Biological Processes -4.31351457 5 More
GO:0032098 regulation of appetite GO Biological Processes -7.13135320 9 More
GO:0032099 negative regulation of appetite GO Biological Processes -4.31351457 5 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032104 regulation of response to extracellular stimulus GO Biological Processes -5.26554247 8 More
GO:0032105 negative regulation of response to extracellular stimulus GO Biological Processes -4.31351457 5 More
GO:0032107 regulation of response to nutrient levels GO Biological Processes -5.26554247 8 More
GO:0032108 negative regulation of response to nutrient levels GO Biological Processes -4.31351457 5 More
GO:0032147 activation of protein kinase activity GO Biological Processes -11.6086663 28 More
GO:0032309 icosanoid secretion GO Biological Processes -4.62385244 5 More
GO:0032355 response to estradiol GO Biological Processes -15.3711017 31 More
GO:0032368 regulation of lipid transport GO Biological Processes -34.5766289 54 More
GO:0032371 regulation of sterol transport GO Biological Processes -19.2332049 29 More
GO:0032374 regulation of cholesterol transport GO Biological Processes -19.2332049 29 More
GO:0032386 regulation of intracellular transport GO Biological Processes -4.43340887 15 More
GO:0032388 positive regulation of intracellular transport GO Biological Processes -2.01592226 7 More
GO:0032526 response to retinoic acid GO Biological Processes -5.75287026 10 More
GO:0032655 regulation of interleukin-12 production GO Biological Processes -15.9447313 16 More
GO:0032675 regulation of interleukin-6 production GO Biological Processes -28.2553997 51 More
GO:0032677 regulation of interleukin-8 production GO Biological Processes -20.0046302 33 More
GO:0032680 regulation of tumor necrosis factor production GO Biological Processes -32.0729913 56 More
GO:0032735 positive regulation of interleukin-12 production GO Biological Processes -12.7826256 12 More
GO:0032755 positive regulation of interleukin-6 production GO Biological Processes -18.6559032 31 More
GO:0032757 positive regulation of interleukin-8 production GO Biological Processes -14.6396218 15 More
GO:0032760 positive regulation of tumor necrosis factor production GO Biological Processes -21.1788990 23 More
GO:0032768 regulation of monooxygenase activity GO Biological Processes -14.2762890 21 More
GO:0032787 monocarboxylic acid metabolic process GO Biological Processes -19.1871601 38 More
GO:0032814 regulation of natural killer cell activation GO Biological Processes -6.02130395 7 More
GO:0032868 response to insulin GO Biological Processes -11.6850377 35 More
GO:0032869 cellular response to insulin stimulus GO Biological Processes -9.16399556 26 More
GO:0032870 cellular response to hormone stimulus GO Biological Processes -24.7707938 79 More
GO:0032872 regulation of stress-activated MAPK cascade GO Biological Processes -11.6818048 20 More
GO:0032874 positive regulation of stress-activated MAPK cascade GO Biological Processes -9.63549885 15 More
GO:0032890 regulation of organic acid transport GO Biological Processes -14.1608908 23 More
GO:0032891 negative regulation of organic acid transport GO Biological Processes -5.29413319 5 More
GO:0032940 secretion by cell GO Biological Processes -8.42144465 43 More
GO:0032944 regulation of mononuclear cell proliferation GO Biological Processes -24.6915018 34 More
GO:0032946 positive regulation of mononuclear cell proliferation GO Biological Processes -20.2231223 25 More
GO:0033157 regulation of intracellular protein transport GO Biological Processes -4.35957871 12 More
GO:0033273 response to vitamin GO Biological Processes -22.1296854 31 More
GO:0033500 carbohydrate homeostasis GO Biological Processes -23.7918768 50 More
GO:0033591 response to L-ascorbic acid GO Biological Processes -4.49239295 3 More
GO:0033674 positive regulation of kinase activity GO Biological Processes -29.8538991 87 More
GO:0034103 regulation of tissue remodeling GO Biological Processes -21.5631413 32 More
GO:0034284 response to monosaccharide GO Biological Processes -18.9205843 39 More
GO:0034440 lipid oxidation GO Biological Processes -3.19555965 6 More
GO:0034637 cellular carbohydrate biosynthetic process GO Biological Processes -1.64538233 3 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034763 negative regulation of transmembrane transport GO Biological Processes -22.14661 42 More
GO:0035150 regulation of tube size GO Biological Processes -44.5138102 41 More
GO:0035239 tube morphogenesis GO Biological Processes -44.2569269 123 More
GO:0035265 organ growth GO Biological Processes -9.67739919 20 More
GO:0035296 regulation of tube diameter GO Biological Processes -44.6572858 41 More
GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway GO Biological Processes -4.70690316 6 More
GO:0035592 establishment of protein localization to extracellular region GO Biological Processes -3.38827795 7 More
GO:0035904 aorta development GO Biological Processes -5.36863544 12 More
GO:0036293 response to decreased oxygen levels GO Biological Processes -40.9544531 79 More
GO:0040007 growth GO Biological Processes -14.0580178 53 More
GO:0040008 regulation of growth GO Biological Processes -30.7609323 104 More
GO:0042102 positive regulation of T cell proliferation GO Biological Processes -13.4787271 17 More
GO:0042110 T cell activation GO Biological Processes -7.78997285 18 More
GO:0042129 regulation of T cell proliferation GO Biological Processes -18.0871480 25 More
GO:0042269 regulation of natural killer cell mediated cytotoxicity GO Biological Processes -3.48241215 5 More
GO:0042306 regulation of protein import into nucleus GO Biological Processes -4.66703664 11 More
GO:0042307 positive regulation of protein import into nucleus GO Biological Processes -4.02622258 5 More
GO:0042445 hormone metabolic process GO Biological Processes -9.53279610 17 More
GO:0042509 regulation of tyrosine phosphorylation of STAT protein GO Biological Processes -19.4049069 20 More
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein GO Biological Processes -19.8380655 19 More
GO:0042593 glucose homeostasis GO Biological Processes -23.8963802 50 More
GO:0042698 ovulation cycle GO Biological Processes -6.53718605 9 More
GO:0042755 eating behavior GO Biological Processes -2.15943760 3 More
GO:0042886 amide transport GO Biological Processes -5.62242821 10 More
GO:0043065 positive regulation of apoptotic process GO Biological Processes -46.1285536 112 More
GO:0043068 positive regulation of programmed cell death GO Biological Processes -46.5713594 114 More
GO:0043255 regulation of carbohydrate biosynthetic process GO Biological Processes -8.87798147 21 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043270 positive regulation of ion transport GO Biological Processes -23.5832054 34 More
GO:0043271 negative regulation of ion transport GO Biological Processes -19.3914052 40 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0043434 response to peptide hormone GO Biological Processes -26.1739008 69 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0043931 ossification involved in bone maturation GO Biological Processes -4.01931275 4 More
GO:0044057 regulation of system process GO Biological Processes -61.6610386 136 More
GO:0044058 regulation of digestive system process GO Biological Processes -4.95295157 10 More
GO:0044060 regulation of endocrine process GO Biological Processes -7.84992769 12 More
GO:0044070 regulation of anion transport GO Biological Processes -12.6410846 24 More
GO:0044242 cellular lipid catabolic process GO Biological Processes -5.52561510 12 More
GO:0044262 cellular carbohydrate metabolic process GO Biological Processes -2.06537786 14 More
GO:0044282 small molecule catabolic process GO Biological Processes -3.48227578 13 More
GO:0044283 small molecule biosynthetic process GO Biological Processes -16.6163676 33 More
GO:0044320 cellular response to leptin stimulus GO Biological Processes -4.28303352 4 More
GO:0044321 response to leptin GO Biological Processes -5.08699974 5 More
GO:0044703 multi-organism reproductive process GO Biological Processes -20.5752550 28 More
GO:0044706 multi-multicellular organism process GO Biological Processes -20.0155761 28 More
GO:0045088 regulation of innate immune response GO Biological Processes -6.98001665 16 More
GO:0045123 cellular extravasation GO Biological Processes -12.7826256 12 More
GO:0045137 development of primary sexual characteristics GO Biological Processes -5.73912217 14 More
GO:0045321 leukocyte activation GO Biological Processes -25.4958219 48 More
GO:0045471 response to ethanol GO Biological Processes -15.9991788 20 More
GO:0045598 regulation of fat cell differentiation GO Biological Processes -17.6607153 22 More
GO:0045765 regulation of angiogenesis GO Biological Processes -63.6171248 109 More
GO:0045785 positive regulation of cell adhesion GO Biological Processes -29.6368249 50 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0045860 positive regulation of protein kinase activity GO Biological Processes -29.3929160 47 More
GO:0045906 negative regulation of vasoconstriction GO Biological Processes -5.18389496 5 More
GO:0045927 positive regulation of growth GO Biological Processes -20.3035639 52 More
GO:0046165 alcohol biosynthetic process GO Biological Processes -3.02044097 6 More
GO:0046324 regulation of glucose import GO Biological Processes -14.8736114 22 More
GO:0046325 negative regulation of glucose import GO Biological Processes -8.14754197 9 More
GO:0046395 carboxylic acid catabolic process GO Biological Processes -2.87762227 9 More
GO:0046425 regulation of receptor signaling pathway via JAK-STAT GO Biological Processes -10.5317026 20 More
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT GO Biological Processes -10.8890337 15 More
GO:0046545 development of primary female sexual characteristics GO Biological Processes -5.43927805 9 More
GO:0046626 regulation of insulin receptor signaling pathway GO Biological Processes -7.79385832 16 More
GO:0046628 positive regulation of insulin receptor signaling pathway GO Biological Processes -3.92081595 4 More
GO:0046649 lymphocyte activation GO Biological Processes -10.1732143 26 More
GO:0046660 female sex differentiation GO Biological Processes -6.37740711 11 More
GO:0046822 regulation of nucleocytoplasmic transport GO Biological Processes -4.16168961 8 More
GO:0046824 positive regulation of nucleocytoplasmic transport GO Biological Processes -4.10947470 6 More
GO:0046850 regulation of bone remodeling GO Biological Processes -7.11509809 13 More
GO:0046879 hormone secretion GO Biological Processes -6.27678757 15 More
GO:0046883 regulation of hormone secretion GO Biological Processes -20.4338227 29 More
GO:0046887 positive regulation of hormone secretion GO Biological Processes -9.61661717 24 More
GO:0046888 negative regulation of hormone secretion GO Biological Processes -8.59327523 10 More
GO:0046890 regulation of lipid biosynthetic process GO Biological Processes -16.6841590 23 More
GO:0046903 secretion GO Biological Processes -18.5147167 70 More
GO:0046942 carboxylic acid transport GO Biological Processes -4.62504459 12 More
GO:0048018 receptor ligand activity GO Molecular Functions -91.0736151 101 More
GO:0048511 rhythmic process GO Biological Processes -10.3377021 38 More
GO:0048514 blood vessel morphogenesis GO Biological Processes -39.8784810 93 More
GO:0048534 hematopoietic or lymphoid organ development GO Biological Processes -16.4041704 79 More
GO:0048589 developmental growth GO Biological Processes -14.0580178 53 More
GO:0048608 reproductive structure development GO Biological Processes -16.4007448 61 More
GO:0048638 regulation of developmental growth GO Biological Processes -23.5012496 63 More
GO:0048639 positive regulation of developmental growth GO Biological Processes -14.4198804 35 More
GO:0048799 animal organ maturation GO Biological Processes -4.70812216 5 More
GO:0050670 regulation of lymphocyte proliferation GO Biological Processes -22.6006415 32 More
GO:0050671 positive regulation of lymphocyte proliferation GO Biological Processes -19.1485102 24 More
GO:0050678 regulation of epithelial cell proliferation GO Biological Processes -51.9930445 102 More
GO:0050708 regulation of protein secretion GO Biological Processes -30.3716714 63 More
GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.1120967 60 More
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.9747849 34 More
GO:0050746 regulation of lipoprotein metabolic process GO Biological Processes -2.92766476 3 More
GO:0050796 regulation of insulin secretion GO Biological Processes -13.8348879 19 More
GO:0050810 regulation of steroid biosynthetic process GO Biological Processes -7.92957130 10 More
GO:0050863 regulation of T cell activation GO Biological Processes -20.3209154 36 More
GO:0050865 regulation of cell activation GO Biological Processes -40.6877761 71 More
GO:0050867 positive regulation of cell activation GO Biological Processes -31.2431659 51 More
GO:0050870 positive regulation of T cell activation GO Biological Processes -17.6497748 28 More
GO:0050892 intestinal absorption GO Biological Processes -7.19451595 7 More
GO:0050900 leukocyte migration GO Biological Processes -39.9164759 46 More
GO:0050901 leukocyte tethering or rolling GO Biological Processes -7.04725442 6 More
GO:0050999 regulation of nitric-oxide synthase activity GO Biological Processes -9.05830591 14 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051047 positive regulation of secretion GO Biological Processes -32.2282376 71 More
GO:0051048 negative regulation of secretion GO Biological Processes -20.2278199 42 More
GO:0051051 negative regulation of transport GO Biological Processes -46.8709407 107 More
GO:0051222 positive regulation of protein transport GO Biological Processes -13.8994291 46 More
GO:0051223 regulation of protein transport GO Biological Processes -25.2801266 81 More
GO:0051249 regulation of lymphocyte activation GO Biological Processes -22.6120519 46 More
GO:0051251 positive regulation of lymphocyte activation GO Biological Processes -20.2181987 37 More
GO:0051341 regulation of oxidoreductase activity GO Biological Processes -18.1249013 32 More
GO:0051347 positive regulation of transferase activity GO Biological Processes -26.6059528 90 More
GO:0051427 hormone receptor binding GO Molecular Functions -9.65736435 9 More
GO:0051896 regulation of protein kinase B signaling GO Biological Processes -30.5149255 55 More
GO:0051897 positive regulation of protein kinase B signaling GO Biological Processes -23.7578366 39 More
GO:0051952 regulation of amine transport GO Biological Processes -10.5179624 22 More
GO:0051953 negative regulation of amine transport GO Biological Processes -4.82877039 5 More
GO:0051955 regulation of amino acid transport GO Biological Processes -5.24816080 10 More
GO:0060341 regulation of cellular localization GO Biological Processes -10.5933083 72 More
GO:0060348 bone development GO Biological Processes -12.2474877 36 More
GO:0060612 adipose tissue development GO Biological Processes -1.95805030 3 More
GO:0060840 artery development GO Biological Processes -12.7697342 25 More
GO:0061035 regulation of cartilage development GO Biological Processes -4.43006301 12 More
GO:0061037 negative regulation of cartilage development GO Biological Processes -4.61361828 8 More
GO:0061448 connective tissue development GO Biological Processes -12.1108226 21 More
GO:0061458 reproductive system development GO Biological Processes -16.2516665 61 More
GO:0061756 leukocyte adhesion to vascular endothelial cell GO Biological Processes -8.18952769 7 More
GO:0062012 regulation of small molecule metabolic process GO Biological Processes -26.8746473 69 More
GO:0070201 regulation of establishment of protein localization GO Biological Processes -24.4831554 82 More
GO:0070302 regulation of stress-activated protein kinase signaling cascade GO Biological Processes -11.5600448 20 More
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade GO Biological Processes -9.54226030 15 More
GO:0070482 response to oxygen levels GO Biological Processes -40.7566635 82 More
GO:0070663 regulation of leukocyte proliferation GO Biological Processes -26.8242532 37 More
GO:0070665 positive regulation of leukocyte proliferation GO Biological Processes -21.5362473 27 More
GO:0070977 bone maturation GO Biological Processes -5.08699974 5 More
GO:0071295 cellular response to vitamin GO Biological Processes -7.93931811 10 More
GO:0071300 cellular response to retinoic acid GO Biological Processes -4.69230219 12 More
GO:0071322 cellular response to carbohydrate stimulus GO Biological Processes -12.8816523 25 More
GO:0071326 cellular response to monosaccharide stimulus GO Biological Processes -13.2453179 24 More
GO:0071345 cellular response to cytokine stimulus GO Biological Processes -39.647808 70 More
GO:0071375 cellular response to peptide hormone stimulus GO Biological Processes -15.9961580 44 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:0071407 cellular response to organic cyclic compound GO Biological Processes -19.6857751 39 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0071496 cellular response to external stimulus GO Biological Processes -17.0078490 52 More
GO:0071692 protein localization to extracellular region GO Biological Processes -3.24312735 14 More
GO:0071695 anatomical structure maturation GO Biological Processes -11.1692541 20 More
GO:0071715 icosanoid transport GO Biological Processes -4.05681596 5 More
GO:0072329 monocarboxylic acid catabolic process GO Biological Processes -2.02717768 5 More
GO:0080135 regulation of cellular response to stress GO Biological Processes -19.0128542 89 More
GO:0090066 regulation of anatomical structure size GO Biological Processes -32.7608623 52 More
GO:0090087 regulation of peptide transport GO Biological Processes -16.3568662 23 More
GO:0090276 regulation of peptide hormone secretion GO Biological Processes -16.6841590 23 More
GO:0090278 negative regulation of peptide hormone secretion GO Biological Processes -6.46280795 7 More
GO:0090316 positive regulation of intracellular protein transport GO Biological Processes -2.57210479 7 More
GO:0097305 response to alcohol GO Biological Processes -17.4096682 46 More
GO:0097696 receptor signaling pathway via STAT GO Biological Processes -5.66899995 7 More
GO:0097746 blood vessel diameter maintenance GO Biological Processes -44.6572858 41 More
GO:0098609 cell-cell adhesion GO Biological Processes -15.7963965 69 More
GO:0098868 bone growth GO Biological Processes -4.61361828 8 More
GO:0110148 biomineralization GO Biological Processes -9.16361193 13 More
GO:0120161 regulation of cold-induced thermogenesis GO Biological Processes -19.1025541 38 More
GO:0120162 positive regulation of cold-induced thermogenesis GO Biological Processes -19.5569802 32 More
GO:0140352 export from cell GO Biological Processes -8.94733589 48 More
GO:1900076 regulation of cellular response to insulin stimulus GO Biological Processes -8.81141992 11 More
GO:1900078 positive regulation of cellular response to insulin stimulus GO Biological Processes -3.69512980 4 More
GO:1900180 regulation of protein localization to nucleus GO Biological Processes -3.85830967 16 More
GO:1900182 positive regulation of protein localization to nucleus GO Biological Processes -4.19203093 7 More
GO:1900744 regulation of p38MAPK cascade GO Biological Processes -6.86981007 8 More
GO:1900745 positive regulation of p38MAPK cascade GO Biological Processes -6.802042 7 More
GO:1901342 regulation of vasculature development GO Biological Processes -64.8504074 111 More
GO:1901615 organic hydroxy compound metabolic process GO Biological Processes -22.7091625 41 More
GO:1901617 organic hydroxy compound biosynthetic process GO Biological Processes -2.99916656 8 More
GO:1901652 response to peptide GO Biological Processes -34.9047734 89 More
GO:1901653 cellular response to peptide GO Biological Processes -21.5212108 58 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
GO:1902652 secondary alcohol metabolic process GO Biological Processes -19.9585075 23 More
GO:1903037 regulation of leukocyte cell-cell adhesion GO Biological Processes -23.2079690 66 More
GO:1903039 positive regulation of leukocyte cell-cell adhesion GO Biological Processes -20.7355312 32 More
GO:1903131 mononuclear cell differentiation GO Biological Processes -9.35861236 21 More
GO:1903522 regulation of blood circulation GO Biological Processes -44.9821911 79 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903531 negative regulation of secretion by cell GO Biological Processes -17.4034654 36 More
GO:1903532 positive regulation of secretion by cell GO Biological Processes -27.9542102 63 More
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -32.3948799 57 More
GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -20.7768498 23 More
GO:1903829 positive regulation of protein localization GO Biological Processes -12.9651258 57 More
GO:1904478 regulation of intestinal absorption GO Biological Processes -5.14025860 6 More
GO:1904729 regulation of intestinal lipid absorption GO Biological Processes -4.31351457 5 More
GO:1904892 regulation of receptor signaling pathway via STAT GO Biological Processes -12.9980471 24 More
GO:1904894 positive regulation of receptor signaling pathway via STAT GO Biological Processes -11.2917234 16 More
GO:1904951 positive regulation of establishment of protein localization GO Biological Processes -13.0308630 46 More
GO:1905952 regulation of lipid localization GO Biological Processes -40.6150331 64 More
GO:1905953 negative regulation of lipid localization GO Biological Processes -25.1573575 31 More
GO:2000377 regulation of reactive oxygen species metabolic process GO Biological Processes -19.1025541 38 More
GO:2000379 positive regulation of reactive oxygen species metabolic process GO Biological Processes -15.0445998 16 More
KEGG pathways: 6 records
KEGG Description Category LogP Number of genes Detail
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
hsa04152 AMPK signaling pathway KEGG Pathway -7.66810818 12 More
hsa04630 JAK-STAT signaling pathway KEGG Pathway -14.4088859 21 More
hsa04920 Adipocytokine signaling pathway KEGG Pathway -10.4150431 19 More
hsa04932 Non-alcoholic fatty liver disease KEGG Pathway -11.2628136 17 More
Drug-Gene interaction
view
Related drugs: 15 records
Drug name Interaction type Source PMID View
bromocriptine NCI 12088923 view
carvedilol NCI 14966787 view
clozapine NCI 12755665 view
felodipine NCI 16097363 view
gemfibrozil NCI 1008376515114521 view
lamivudine NCI 16091072 view
lovastatin NCI 10083765 view
methadone NCI 15717844 view
methimazole NCI 10495413 view
mirtazapine NCI 12518269 view
olanzapine PharmGKB 18681781 view
propylthiouracil NCI 12450621 view
risperidone NCIPharmGKB 1987368412755665215107672379952826880915 view
soybean oil NCI 10726911 view
troglitazone NCI 10753628 view
Related studies: 18 records
Molecular factor Omics type Application Objective MI type Reference
NM_000230.3:c.-2548G>A genomics myocardial infarction[diagnosis] myocardial infarction Roszkowska-Gancarz M et al. Endokrynol Pol. 2014
leptin proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Soderberg S et al. J Intern Med. 1999
leptin proteomics interleukin-6[other] acute ST elevation myocardial infarction Fujimaki S et al. J Int Med Res. 2001
leptin proteomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Meisel SR et al. Cardiology. 2001
leptin proteomics myocardial infarction[diagnosis] myocardial infarction Wallerstedt SM et al. Blood Press. 2004
leptin proteomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Jose VJ et al. Indian Heart J. 2005
leptin proteomics acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Taneli F et al. Angiology. 2006
leptin proteomics obesity[other] acute myocardial infarction Piestrzeniewicz K et al. Cardiol J. 2007
leptin proteomics glucose intolerance[prognosis (bad)] acute myocardial infarction Wallander M et al. Diabet Med. 2008
leptin proteomics cardiovascular adverse events[prognosis (bad)] acute myocardial infarction Wallander M et al. Diabet Med. 2008
leptin proteomics type 2 diabetes mellitus[prognosis (bad)] acute myocardial infarction Krasnodebski P et al. Kardiol Pol. 2010
leptin proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Gundala R et al. J Periodontol. 2014
leptin proteomics left ventricular ejection fraction[other] acute myocardial infarction Khafaji HA et al. BMC Res Notes. 2012
leptin proteomics adverse events[prognosis (bad)] acute myocardial infarction Morita Y et al. Circ J. 2013
leptin proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Syed AH et al. Cureus. 2020
leptin proteomics myocardial infarction[diagnosis] myocardial infarction Sierra-Johnson J et al. Am J Cardiol. 2007
leptin proteomics myocardial infarction[diagnosis] myocardial infarction Sierra-Johnson J et al. Am J Cardiol. 2007
leptin proteomics poor predictor type 2 diabetes mellitus[prognosis (bad)] ST elevation myocardial infarction Barbarash O et al. Arch Med Sci. 2017
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